NAC study UK

Titel: NAC N-Acetylcysteine in patients with Sickle Cell Disease, Reducing the incidence of daily life pain in patients with sickle cell disease A Multicenter Randomized Placebo Controlled Trial

General study documents

• Protocol (4.0 UK)
• Blood sampling and laboratory manual
• Pharmacy manual regarding N-Acetylcysteine and placebo
• Study checklist
• Study data sheets
• CRF instructions
• Enrolment log

• Registration form
• Randomisation form
• SAE form
• SAE guidelines 
• Procedure for deblinding
• Slide show initiation site visit london

Patient informed consents

• Patient information
• Informed consent sheet

Pain diary

• Pain diary for patients > 18 jr

Questionnaires

• Questionnaire for patients > 18 jr: evaluation at baseline

• Questionnaire for patients > 18 jr: evaluation at 3 - 6 months